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Article

Mass spectrometric analysis of dimer-disrupting mutations in Plasmodium triosephosphate isomerase.

Analytical biochemistry - 1 May 2016

Bandyopadhyay Debarati, Prakash Sunita, Gupta Kallol, Balaram Padmanabhan

Abstract excerpt

Electrospray ionization mass spectrometry (ESI MS) under nanospray conditions has been used to examine the effects of mutation at two key dimer interface residues, Gln (Q) 64 and Thr (T) 75, in Plasmodium falciparum triosephosphate isomerase. Both residues participate in an intricate network of intra- and intersubunit hydrogen bonds. The gas phase distributions of dimeric and monomeric protein species have been...

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PMID: 26919806
DOI: 10.1016/j.ab.2016.02.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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