Article
Unbiased targeted next-generation sequencing molecular approach for primary immunodeficiency diseases.
The Journal of allergy and clinical immunology - 1 Jun 2016
Al-Mousa Hamoud, Abouelhoda Mohamed, Monies Dorota M, Al-Tassan Nada, Al-Ghonaium Abdulaziz, Al-Saud Bandar, Al-Dhekri Hasan, Arnaout Rand, Al-Muhsen Saleh, Ades Nazema, Elshorbagi Sahar, Al Gazlan Sulaiman, Sheikh Farrukh, Dasouki Majed, El-Baik Lina, Elamin Tanzeil, Jaber Amal, Kheir Omnia, El-Kalioby Mohamed, Subhani Shazia, Al Idrissi Eman, Al-Zahrani Mofareh, Alhelale Maryam, Alnader Noukha, Al-Otaibi Afaf, Kattan Rana, Al Abdelrahman Khalid, Al Breacan Muna M, Bin Humaid Faisal S, Wakil Salma Majid, Alzayer Fadi, Al-Dusery Haya, Faquih Tariq, Al-Hissi Safa, Meyer Brian F, Hawwari Abbas
Abstract excerpt
BACKGROUND: Molecular genetics techniques are an essential diagnostic tool for primary immunodeficiency diseases (PIDs). The use of next-generation sequencing (NGS) provides a comprehensive way of concurrently screening a large number of PID genes. However, its validity and cost-effectiveness require verification. OBJECTIVES: We sought to identify and overcome complications associated with the use of NGS in a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.