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Article

Macrophage precursor cells from the left atrial appendage of the heart spontaneously reprogram into a C-kit+/CD45- stem cell-like phenotype.

International journal of cardiology - 15 Apr 2016

Leinonen Jussi V, Korkus-Emanuelov Avishag, Wolf Yochai, Milgrom-Hoffman Michal, Lichtstein David, Hoss Sara, Lotan Chaim, Tzahor Eldad, Jung Steffen, Beeri Ronen

Abstract excerpt

BACKGROUND: The developmental origin of the c-kit expressing progenitor cell pool in the adult heart has remained elusive. Recently, it has been discovered that the injured heart is enriched with c-kit(+) cells, which also express the hematopoietic marker CD45. METHODS AND RESULTS: In this study, we characterize the phenotype and transcriptome of the c-kit+/CD45+/CD11b+/Flk-1+/Sca-1±(B-type) cell population,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26913371
DOI: 10.1016/j.ijcard.2016.02.040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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