Article
Managing Drug Resistance in Cancer: Role of Cancer Informatics.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Gautam Ankur, Chaudhary Kumardeep, Kumar Rahul, Gupta Sudheer, Singh Harinder, Raghava Gajendra P S
Abstract excerpt
Understanding and managing cancer drug resistance is the main goal of the modern oncology programs worldwide. One of the major factors contributing to drug resistance in cancer cells is the acquired mutations in drug targets. Advances in sequencing technologies and high-throughput screening assays have generated huge information related to pharmaco-profiling of anticancer drugs and revealed the mutational...
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