Article
Single Gene Prognostic Biomarkers in Ovarian Cancer: A Meta-Analysis.
PloS one - 1 Jan 2016
Willis Scooter, Villalobos Victor M, Gevaert Olivier, Abramovitz Mark, Williams Casey, Sikic Branimir I, Leyland-Jones Brian
Abstract excerpt
PURPOSE: To discover novel prognostic biomarkers in ovarian serous carcinomas. METHODS: A meta-analysis of all single genes probes in the TCGA and HAS ovarian cohorts was performed to identify possible biomarkers using Cox regression as a continuous variable for overall survival. Genes were ranked by p-value using Stouffer's method and selected for statistical significance with a false discovery rate (FDR) <.05...
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