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Article

FBXO7 mutations in Parkinson's disease and multiple system atrophy.

Neurobiology of aging - 1 Apr 2016

Conedera Silvio, Apaydin Hulya, Li Yuanzhe, Yoshino Hiroyo, Ikeda Aya, Matsushima Takashi, Funayama Manabu, Nishioka Kenya, Hattori Nobutaka

Abstract excerpt

Mutations in the F-box only protein 7 (FBXO7) gene, located on chromosome 22q12-q13, have recently been identified as having distinct clinical features in patients with hereditary Parkinson's disease (PD). Pathologically, α-synuclein-positive inclusions have been identified using anti-FBXO7 antibody staining techniques. In the present study, we screened entire exons of FBXO7 from 271 patients (231 PD and 40...

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Source

Identifiers

PMID: 26882974
DOI: 10.1016/j.neurobiolaging.2016.01.003

Genes

FBXO7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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