Article
Attenuation of DMBA/croton oil induced mouse skin papilloma by Apodytes dimidiata mediated by its antioxidant and antimutagenic potential.
Pharmaceutical biology - 1 Sept 2016
Divya Menon K, Salini Sasidharan, Meera Nair, Lincy Lawrence, Seema Menon, Raghavamenon Achuthan C, Babu Thekkekara D
Abstract excerpt
Context Considering the role of cellular oxidative stress in mutations and subsequent transformation, phytochemicals with antioxidant potential has become a primary choice as chemopreventives. Apodytes dimidiata E. Mey. Ex. Arn (Icacinaceae), a widely used plant in Zulu traditional medicine, is reported to possess antioxidant activity. Objective To investigate the chemopreventive efficacy of methanol extract of...
Topics
- 9,10-Dimethyl-1,2-benzanthracene
- Animals
- Anticarcinogenic Agents
- Antimutagenic Agents
- Antioxidants
- Catalase
- Cell Transformation, Neoplastic
- Croton Oil
- Dose-Response Relationship, Drug
- Gas Chromatography-Mass Spectrometry
