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Maximal gene number maintainable by stochastic correction - The second error threshold.

Journal of theoretical biology - 21 Sept 2016

Hubai András G, Kun Ádám

Abstract excerpt

There is still no general solution to Eigen׳s Paradox, the chicken-or-egg problem of the origin of life: neither accurate copying, nor long genomes could have evolved without one another being established beforehand. But an array of small, individually replicating genes might offer a workaround, provided that multilevel selection assists the survival of the ensemble. There are two key difficulties that such a...

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PMID: 26876752
DOI: 10.1016/j.jtbi.2016.02.007

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