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Article

MAPK1/ERK2 as novel target genes for pain in head and neck cancer patients.

BMC genetics - 13 Feb 2016

Reyes-Gibby Cielito C, Wang Jian, Silvas Mary Rose T, Yu Robert, Yeung Sai-Ching J, Shete Sanjay

Abstract excerpt

BACKGROUND: Genetic susceptibility plays an important role in the risk of developing pain in individuals with cancer. As a complex trait, multiple genes underlie this susceptibility. We used gene network analyses to identify novel target genes associated with pain in patients newly diagnosed with squamous cell carcinoma of the head and neck (HNSCC). RESULTS: We first identified 36 cancer pain-related genes (i.e.,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26872611
DOI: 10.1186/s12863-016-0348-7
PMCID: PMC4752805

Genes

MAPK1
PDGFC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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