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Regulation of the tumour suppressor PDCD4 by miR-499 and miR-21 in oropharyngeal cancers

11 Feb 2016

Abstract excerpt

BACKGROUND: The rates of oropharyngeal cancers such as tonsil cancers are increasing. The tumour suppressor protein Programmed Cell Death Protein 4 (PDCD4) has been implicated in the development of various human cancers and small RNAs such as microRNAs (miRNAs) can regulate its expression. However the exact regulation of PDCD4 by multiple miRNAs in oropharyngeal squamous cell carcinoma (SCC) is not well...

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PMID: 26867589
DOI: 10.1186/s12885-016-2109-4

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