Whole genome sequence analysis of BT-474 using complete Genomics' standard and long fragment read technologies.

doi:10.1186/s13742-016-0113-x

Article

Whole genome sequence analysis of BT-474 using complete Genomics' standard and long fragment read technologies.

GigaScience - 1 Jan 2016

Ciotlos Serban, Mao Qing, Zhang Rebecca Yu, Li Zhenyu, Chin Robert, Gulbahce Natali, Liu Sophie Jia, Drmanac Radoje, Peters Brock A

Abstract excerpt

BACKGROUND: The cell line BT-474 is a popular cell line for studying the biology of cancer and developing novel drugs. However, there is no complete, published genome sequence for this highly utilized scientific resource. In this study we sought to provide a comprehensive and useful data set for the scientific community by generating a whole genome sequence for BT-474. FINDINGS: Five μg of genomic DNA, isolated...

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