Article
Tuning of Hemes b Equilibrium Redox Potential Is Not Required for Cross-Membrane Electron Transfer.
The Journal of biological chemistry - 25 Mar 2016
Pintscher Sebastian, Kuleta Patryk, Cieluch Ewelina, Borek Arkadiusz, Sarewicz Marcin, Osyczka Artur
Abstract excerpt
In biological energy conversion, cross-membrane electron transfer often involves an assembly of two hemesb The hemes display a large difference in redox midpoint potentials (ΔEm_b), which in several proteins is assumed to facilitate cross-membrane electron transfer and overcome a barrier of membrane potential. Here we challenge this assumption reporting on hemebligand mutants of cytochromebc1in which, for the...
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