Article
HLA-DQA1/B1 alleles as putative susceptibility markers in congenital toxoplasmosis.
Virulence - 18 May 2016
Shimokawa Paulo Tadashi, Targa Lília Spaleta, Yamamoto Lidia, Rodrigues Jonatas Cristian, Kanunfre Kelly Aparecida, Okay Thelma Suely
Abstract excerpt
Host and parasite genotypes are among the factors associated with congenital toxoplasmosis pathogenesis. As HLA class II molecules play a key role in the immune system regulation, the aim of this study was to investigate whether HLA-DQA1/B1 alleles are associated with susceptibility or protection to congenital toxoplasmosis. One hundred and twenty-two fetuses with and 103 without toxoplasmosis were studied. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
