Article
Tissue-resident memory T cells in cytomegalovirus infection.
Current opinion in virology - 1 Feb 2016
Thom Jenny Tosca, Oxenius Annette
Abstract excerpt
Herpesviruses establish life-long infection in their hosts and maintain latent reservoirs for sporadic reactivation at peripheral sites, such as skin and mucosae. For herpes simplex virus infection, experimental studies in mice revealed that immediate protection against local reactivation or superinfection events in the skin relies on tissue resident memory T cells (TRM) rather than on their circulating...
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