Article
Neurofibromatosis as a gateway to better treatment for a variety of malignancies.
Progress in neurobiology - 1 May 2017
Bakker Annette C, La Rosa Salvatore, Sherman Larry S, Knight Pamela, Lee Hyerim, Pancza Patrice, Nievo Marco
Abstract excerpt
The neurofibromatoses (NF) are a group of rare genetic disorders that can affect all races equally at an incidence from 1:3000 (NF1) to a log unit lower for NF2 and schwannomatosis. Since the research community is reporting an increasing number of malignant cancers that carry mutations in the NF genes, the general interest of both the research and pharma community is increasing and the authors saw an opportunity...
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