[Neurofibromatosis--an inborn genetic disorder with susceptibility to neoplasia].

Abstract excerpt

Among different subtypes of neurofibromatosis (Nf), type 1 (Nf-1) predominates in frequency (approximately 97% of Nfs' patients) with an incidence of approximately 1 in 3500 live births. Nf-2, comprises 2% of the Nf population and is a very rare disease (1:40,000). Both are autosomal dominant disorders with 100% penetration, variable expression and 50% rate of new (de novo) mutations. The protein products of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genes, Neurofibromatosis 1
• Share to Genes, Neurofibromatosis 2
• Share to Neurofibromatoses