Article
Lectin binding of human sperm associates with DEFB126 mutation and serves as a potential biomarker for subfertility.
Scientific reports - 1 Feb 2016
Xin Aijie, Cheng Li, Diao Hua, Wu Yancheng, Zhou Shumin, Shi Changgen, Sun Yangyang, Wang Peng, Duan Shiwei, Zheng Jufen, Wu Bin, Yuan Yao, Gu Yihua, Chen Guowu, Sun Xiaoxi, Shi Huijuan, Tao Shengce, Zhang Yonglian
Abstract excerpt
Coating on the sperm surface, glycocalyx, plays a key role in sperm motility, maturation and fertilization. A comprehensive profile of sperm surface glycans will greatly facilitate both basic researches and clinical studies. Because of the capability of recognizing different glycan moieties, lectins are widely used in glycobiology. However, lacking high-throughput technology, limited lectins have been reported...
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