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Hierarchy of cellular decisions in collective behavior: Implications for wound healing

2 Feb 2016

Abstract excerpt

Collective processes such as wound re-epithelialization result from the integration of individual cellular decisions. To determine which individual cell behaviors represent the most promising targets to engineer re-epithelialization, we examined collective and individual responses of HaCaT keratinocytes seeded upon polyacrylamide gels of three stiffnesses (1, 30, and 100 kPa) and treated with a range of epidermal...

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PMID: 26832302
DOI: 10.1038/srep20139

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