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Development of a Three Dimensional Multiscale Computational Model of the Human Epidermis

13 Jan 2010

Abstract excerpt

Transforming Growth Factor (TGF-beta1) is a member of the TGF-beta superfamily ligand-receptor network. and plays a crucial role in tissue regeneration. The extensive in vitro and in vivo experimental literature describing its actions nevertheless describe an apparent paradox in that during re-epithelialisation it acts as proliferation inhibitor for keratinocytes. The majority of biological models focus on...

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PMID: 20076760
DOI: 10.1371/journal.pone.0008511

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