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Article

Involvement of homocysteine, homocysteine thiolactone, and paraoxonase type 1 (<scp>PON</scp>‐1) in the etiology of defective human sperm function

29 Jan 2016

Abstract excerpt

This study reports, for the first time, the significant (p ≤ 0.01) accumulation of homocysteine residues in low density, defective sperm suspensions isolated from patients attending an infertility clinic. This overabundance of homocysteine was not related to a deficiency in folate availability but may have been a reflection of the oxidative stress that characterizes such defective sperm populations. Direct...

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PMID: 26825875
DOI: 10.1111/andr.12157

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