Article
Recognition of genetic predisposition in pediatric cancer patients: An easy-to-use selection tool.
European journal of medical genetics - 1 Mar 2016
Jongmans Marjolijn C J, Loeffen Jan L C M, Waanders Esmé, Hoogerbrugge Peter M, Ligtenberg Marjolijn J L, Kuiper Roland P, Hoogerbrugge Nicoline
Abstract excerpt
Genetic predisposition for childhood cancer is under diagnosed. Identifying these patients may lead to therapy adjustments in case of syndrome-related increased toxicity or resistant disease and syndrome-specific screening programs may lead to early detection of a further independent malignancy. Cancer surveillance might also be warranted for affected relatives and detection of a genetic mutation can allow for...
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