Article
Successful switch from insulin to oral sulfonylurea therapy in HNF1A-MODY Tunisian patient with the P291fsinsC mutation.
Diabetes research and clinical practice - 1 May 2016
Khelifa Souhaïra Ben, Dendana Azza, Barboura Ilhem, Khochtali Ines, Chahed Hinda, Ferchichi Selima, Miled Abdelhedi
Abstract excerpt
The hot spot mutation P291fsinsC was identified for the first time in a 26 years old Tunisian woman. The low serum level of high C-reactive protein was helpful to target the HNF1A gene. Due to the molecular diagnosis, the change from insulin to sulfonylurea therapy was performed successfully.
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