Article
Detecting Staphylococcus aureus Virulence and Resistance Genes: a Comparison of Whole-Genome Sequencing and DNA Microarray Technology.
Journal of clinical microbiology - 1 Apr 2016
Strauß Lena, Ruffing Ulla, Abdulla Salim, Alabi Abraham, Akulenko Ruslan, Garrine Marcelino, Germann Anja, Grobusch Martin Peter, Helms Volkhard, Herrmann Mathias, Kazimoto Theckla, Kern Winfried, Mandomando Inácio, Peters Georg, Schaumburg Frieder, von Müller Lutz, Mellmann Alexander
Abstract excerpt
Staphylococcus aureusis a major bacterial pathogen causing a variety of diseases ranging from wound infections to severe bacteremia or intoxications. Besides host factors, the course and severity of disease is also widely dependent on the genotype of the bacterium. Whole-genome sequencing (WGS), followed by bioinformatic sequence analysis, is currently the most extensive genotyping method available. To identify...
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