Article
Multiplex families with epilepsy: Success of clinical and molecular genetic characterization.
Neurology - 23 Feb 2016
Afawi Zaid, Oliver Karen L, Kivity Sara, Mazarib Aziz, Blatt Ilan, Neufeld Miriam Y, Helbig Katherine L, Goldberg-Stern Hadassa, Misk Adel J, Straussberg Rachel, Walid Simri, Mahajnah Muhammad, Lerman-Sagie Tally, Ben-Zeev Bruria, Kahana Esther, Masalha Rafik, Kramer Uri, Ekstein Dana, Shorer Zamir, Wallace Robyn H, Mangelsdorf Marie, MacPherson James N, Carvill Gemma L, Mefford Heather C, Jackson Graeme D, Scheffer Ingrid E, Bahlo Melanie, Gecz Jozef, Heron Sarah E, Corbett Mark, Mulley John C, Dibbens Leanne M, Korczyn Amos D, Berkovic Samuel F
Abstract excerpt
OBJECTIVE: To analyze the clinical syndromes and inheritance patterns of multiplex families with epilepsy toward the ultimate aim of uncovering the underlying molecular genetic basis. METHODS: Following the referral of families with 2 or more relatives with epilepsy, individuals were classified into epilepsy syndromes. Families were classified into syndromes where at least 2 family members had a specific...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.