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Article

Screening of the SLC17A8 gene as a causative factor for autosomal dominant non-syndromic hearing loss in Koreans.

BMC medical genetics - 22 Jan 2016

Ryu Nari, Sagong Borum, Park Hong-Joon, Kim Min-A, Lee Kyu-Yup, Choi Jae Young, Kim Un-Kyung

Abstract excerpt

BACKGROUND: One of the causes of sensorineural hearing loss (SNHL) is degeneration of the inner hair cells in the organ of Corti in the cochlea. The SLC17A8 (solute carrier family 17, member 8) gene encodes vesicular glutamate transporter 3 (VGLUT3), and among its isoforms (VGLUT1-3), only VGLUT3 is expressed selectively in the inner hair cells (IHCs). VGLUT3 transports the neurotransmitter glutamate into the...

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Identifiers

PMID: 26797701
DOI: 10.1186/s12881-016-0269-3
PMCID: PMC4722616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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