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Article

Mitochondrial DNA variants correlate with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome.

Journal of translational medicine - 20 Jan 2016

Billing-Ross Paul, Germain Arnaud, Ye Kaixiong, Keinan Alon, Gu Zhenglong, Hanson Maureen R

Abstract excerpt

BACKGROUND: Mitochondrial dysfunction has been hypothesized to occur in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a disease characterized by fatigue, cognitive difficulties, pain, malaise, and exercise intolerance. We investigated whether haplogroup, single nucleotide polymorphisms (SNPs), or heteroplasmy of mitochondrial DNA (mtDNA) were associated with health status and/or symptoms. METHODS:...

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Identifiers

PMID: 26791940
DOI: 10.1186/s12967-016-0771-6
PMCID: PMC4719218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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