Article
Interferon-gamma improves impaired dentinogenic and immunosuppressive functions of irreversible pulpitis-derived human dental pulp stem cells.
Scientific reports - 18 Jan 2016
Sonoda Soichiro, Yamaza Haruyoshi, Ma Lan, Tanaka Yosuke, Tomoda Erika, Aijima Reona, Nonaka Kazuaki, Kukita Toshio, Shi Songtao, Nishimura Fusanori, Yamaza Takayoshi
Abstract excerpt
Clinically, irreversible pulpitis is treated by the complete removal of pulp tissue followed by replacement with artificial materials. There is considered to be a high potential for autologous transplantation of human dental pulp stem cells (DPSCs) in endodontic treatment. The usefulness of DPSCs isolated from healthy teeth is limited. However, DPSCs isolated from diseased teeth with irreversible pulpitis...
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