Article
Pre-treatment VD levels and VDR receptors as potential predictors of occurrence and overall survival in paediatric patients with solid tumours-a single institution pilot study.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2016
Bienertová-Vašků Julie, Drábová Klára, Zlámal Filip, Tomandl Josef, Kýr Michal, Šplíchal Zbyněk, Štěrba Jaroslav
Abstract excerpt
Recently, vitamin D has been recognized as an important player in the immune system, and multiple studies suggested its involvement in cancer, too. The aims of this study were to investigate selected single nucleotide polymorphisms (SNPs) in the VDR gene, BsmI (rs1544410; A > G), FokI (rs 2228570; C > T), TaqI (rs731236; T > C), ApaI (rs 7975232; C > T) and Cdx-2 (rs11568820; A > G), and to evaluate their...
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