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An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor

14 Jan 2016

Abstract excerpt

Plants use autophagy to safeguard against infectious diseases. However, how plant pathogens interfere with autophagy-related processes is unknown. Here, we show that PexRD54, an effector from the Irish potato famine pathogen Phytophthora infestans, binds host autophagy protein ATG8CL to stimulate autophagosome formation. PexRD54 depletes the autophagy cargo receptor Joka2 out of ATG8CL complexes and interferes...

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PMID: 26765567
DOI: 10.7554/elife.10856

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