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Article

Screening of HHEX Mutations in Chinese Children with Thyroid Dysgenesis.

Journal of clinical research in pediatric endocrinology - 5 Mar 2016

Liu Shiguo, Chai Jian, Zheng Guohua, Li Huichao, Lu Deguo, Ge Yinlin

Abstract excerpt

OBJECTIVE: Congenital hypothyroidism (CH) is a frequent neonatal endocrine disease with an incidence of about 1:2500 worldwide. Although thyroid dysgenesis (TD) is the most frequent cause of CH cases, its pathogenesis remains unclear. The aim of this study was to screen the hematopoietically-expressedhomeobox gene (HHEX) mutations in Chinese children with TD. METHODS: Genomic deoxyribonucleic acid was extracted...

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Source

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Identifiers

PMID: 26757609
DOI: 10.4274/jcrpe.2456
PMCID: PMC4805044

Genes

HHEX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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