Article
The impact of an interventional counselling procedure in families with a BRCA1/2 gene mutation: efficacy and safety.
Familial cancer - 1 Apr 2016
Sermijn Erica, Delesie Liesbeth, Deschepper Ellen, Pauwels Ingrid, Bonduelle Maryse, Teugels Erik, De Grève Jacques
Abstract excerpt
BACKGROUND: Predictive genetic testing has high impact on cancer prevention for BRCA carriers and passing this information in BRCA families is important. Mostly, this is proband-mediated but this path is defective and denies relatives lifesaving information. OBJECTIVE: To assess the efficacy/safety of an intervention, in which relatives are actively informed. DESIGN: Sequential prospective study in new BRCA...
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