Article
Reassessing the Potential Activities of Plant CGI-58 Protein.
PloS one - 1 Jan 2016
Khatib Abdallah, Arhab Yani, Bentebibel Assia, Abousalham Abdelkarim, Noiriel Alexandre
Abstract excerpt
Comparative Gene Identification-58 (CGI-58) is a widespread protein found in animals and plants. This protein has been shown to participate in lipolysis in mice and humans by activating Adipose triglyceride lipase (ATGL), the initial enzyme responsible for the triacylglycerol (TAG) catabolism cascade. Human mutation of CGI-58 is the cause of Chanarin-Dorfman syndrome, an orphan disease characterized by a systemic...
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