Article
Precision Medicine: Clarity for the Complexity of Dementia.
The American journal of pathology - 1 Mar 2016
Cholerton Brenna, Larson Eric B, Quinn Joseph F, Zabetian Cyrus P, Mata Ignacio F, Keene C Dirk, Flanagan Margaret, Crane Paul K, Grabowski Thomas J, Montine Kathleen S, Montine Thomas J
Abstract excerpt
Three key elements to precision medicine are stratification by risk, detection of pathophysiological processes as early as possible (even before clinical presentation), and alignment of mechanism of action of intervention(s) with an individual's molecular driver(s) of disease. Used for decades in the management of some rare diseases and now gaining broad currency in cancer care, a precision medicine approach is...
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