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Article

miR‑197 promotes the invasion and migration of colorectal cancer by targeting insulin‑like growth factor‑binding protein 3.

Oncology reports - 1 Nov 2018

Zhou Na, Sun Zhao, Li Ningning, Ge Yuping, Zhou Jianfeng, Han Qin, Zhao Lin, Bai Chunmei

Abstract excerpt

The incidence and mortality of colorectal cancer (CRC) have been rising rapidly in China. A number of miRNAs have been confirmed to be involved in diverse biological processes of CRC. However, whether miR‑197 plays a role in migration and invasion of CRC has never been explored. In the present study Transwell chambers were used in in vitro migration and invasion assays. Dual-luciferase reporter assay was employed...

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Identifiers

PMID: 30106114
DOI: 10.3892/or.2018.6640

Genes

IGFBP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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