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Article

Ectopic expression of microRNA-155 enhances innate antiviral immunity against HBV infection in human hepatoma cells

18 Jul 2011

Abstract excerpt

BACKGROUND: Host innate antiviral immunity is the first line of defense against viral infection, and is precisely regulated by thousands of genes at various stages, including microRNAs. MicroRNA-155 (miR-155) was found to be up-regualted during viral infection, and influence the host immune response. Besides, the expression of miR-155, or its functional orthologs, may also contribute to viral oncogenesis. HBV is...

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PMID: 21762537
DOI: 10.1186/1743-422x-8-354

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