Article
Construction of an Efficient Mutant Strain of Trichosporonoides oedocephalis with HOG1 Gene Deletion for Production of Erythritol.
Journal of microbiology and biotechnology - 28 Apr 2016
Li Liangzhi, Yang Tianyi, Guo Weiqiang, Ju Xin, Hu Cuiying, Tang Bingyu, Fu Jiaolong, Gu Jingsheng, Zhang Haiyang
Abstract excerpt
The mitogen-activated protein kinase HOG1 (high-osmolarity glycerol response pathway) plays a crucial role in the response of yeast to hyperosmotic shock. Trichosporonoides oedocephalis produces large amounts of polyols (,e.g., erythritol and glycerol) in a culture medium. However, the effects of HOG1 gene knockout and environmental stress on the production of these polyols have not yet been studied. In this...
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