Article
Sequence variation of 22 autosomal STR loci detected by next generation sequencing.
Forensic science international. Genetics - 1 Mar 2016
Gettings Katherine Butler, Kiesler Kevin M, Faith Seth A, Montano Elizabeth, Baker Christine H, Young Brian A, Guerrieri Richard A, Vallone Peter M
Abstract excerpt
Sequencing short tandem repeat (STR) loci allows for determination of repeat motif variations within the STR (or entire PCR amplicon) which cannot be ascertained by size-based PCR fragment analysis. Sanger sequencing has been used in research laboratories to further characterize STR loci, but is impractical for routine forensic use due to the laborious nature of the procedure in general and additional steps...
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