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Article

Co-occurrence of JAK2 V617F and an uncommon CALR del (p.K368fs*51) mutation facilitates JAK2/STAT signaling in polycythemia vera.

Leukemia & lymphoma - 1 Jul 2016

Xing Chong-Yun, Li Hai-Ying, Wu Jian-Bo, Gao Shen-Meng

Abstract excerpt

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Topics

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Share to Calreticulin
Share to Cell Line, Tumor
Share to DNA Mutational Analysis
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Janus Kinase 2

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Share to Signal Transduction

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Source

Identifiers

PMID: 26701108
DOI: 10.3109/10428194.2015.1115031

Genes

JAK2
CALR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Co-occurrence of JAK2 V617F and an uncommon CALR del (p.K368fs*51) mutation facilitates JAK2/STAT signaling in polycythemia vera.PMID 26701108Read ↗

JAK2V617F and CALR double mutations are more frequently encountered in patients with low JAK2V617F allelic burdens.Semantic proximity Read ↗

JAK2 V617F and CALR mutations are not mutually exclusive; findings from retrospective analysis of a small patient cohort.Semantic proximity Read ↗

A report on the co-occurrence of JAK2V617F and CALR mutations in myeloproliferative neoplasm patients.Semantic proximity Read ↗

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Acquisition of JAK2 V617F to CALR-mutated clones accelerates disease progression and might enhance growth capacity.Semantic proximity Read ↗

JAK2 mutations in polycythemia vera--molecular mechanisms and clinical applications.Semantic proximity Read ↗

JAK2V617F Exon-14 Mutation Driven Polycythemia Vera.Semantic proximity Read ↗

Prevalance of JAK2 V617F and exon 12 mutations in polycythaemia veraSemantic proximity Read ↗

A rare CALR variant mutation and efficient peginterferon alfa-2a response in a patient with essential thrombocythemia.Semantic proximity Read ↗

Erythrocytosis with JAK2 GGCC_46/1 haplotype and without JAK2 V617F mutation is associated with CALR rs1049481_G allele.Semantic proximity Read ↗

The JAK2V617F mutation is acquired secondary to the predisposing alteration in familial polycythaemia veraSemantic proximity Read ↗

Effect of CALR and JAK2 mutations on the clinical and hematological phenotypes of the disease in patients with myelofibrosis - long-term experience from a single center.Semantic proximity Read ↗

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