Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Homologous Recombination Repair Factors Rad51 and BRCA1 Are Necessary for Productive Replication of Human Papillomavirus 31

24 Dec 2015

Abstract excerpt

UNLABELLED: High-risk human papillomavirus 31 (HPV31)-positive cells exhibit constitutive activation of the ATM-dependent DNA damage response (DDR), which is necessary for productive viral replication. In response to DNA double-strand breaks (DSBs), ATM activation leads to DNA repair through homologous recombination (HR), which requires the principal recombinase protein Rad51, as well as BRCA1. Previous studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cervical Cancer and HPV Research
Share to DNA Repair Mechanisms
Share to Polyomavirus and related diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26699641
DOI: 10.1128/jvi.02495-15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Homologous Recombination Repair Factors Rad51 and BRCA1 Are Necessary for Productive Replication of Human Papillomavirus 31PMID 26699641Read ↗

Productive Replication of Human Papillomavirus 31 Requires DNA Repair Factor Nbs1Semantic proximity Read ↗

The Rb binding domain of HPV31 E7 is required to maintain high levels of DNA repair factors in infected cellsSemantic proximity Read ↗

Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and AmplificationSemantic proximity Read ↗

Human Papillomaviruses Recruit Cellular DNA Repair and Homologous Recombination Factors to Viral Replication CentersSemantic proximity Read ↗

High-Risk Alphapapillomavirus Oncogenes Impair the Homologous Recombination PathwaySemantic proximity Read ↗

Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon DifferentiationSemantic proximity Read ↗

Chromatin assembly by the histone chaperone HIRA facilitates Human Papillomavirus replicationSemantic proximity Read ↗

Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNASemantic proximity Read ↗

Human papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNASemantic proximity Read ↗

Engagement of the ATR-Dependent DNA Damage Response at the Human Papillomavirus 18 Replication Centers during the Initial AmplificationSemantic proximity Read ↗

Nuclear Accumulation of the Papillomavirus E1 Helicase Blocks S-Phase Progression and Triggers an ATM-Dependent DNA Damage ResponseSemantic proximity Read ↗

STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus ReplicationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.