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Article

Three faces of recombination activating gene 1 (RAG1) mutations.

Acta microbiologica et immunologica Hungarica - 1 Dec 2015

Patiroglu Turkan, Akar Himmet Haluk, Van Der Burg Mirjam

Abstract excerpt

Severe combined immune deficiency (SCID) is a group of genetic disorder associated with development of T- and/or B-lymphocytes. Recombination-activating genes (RAG1/2) play a critical role on VDJ recombination process that leads to the production of a broad T-cell receptor (TCR) and B-cell receptor (BCR) repertoire in the development of T and B cells. RAG1/2 genes mutations result in various forms of primary...

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Source

Identifiers

PMID: 26689875
DOI: 10.1556/030.62.2015.4.4

Genes

RAG1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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