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Article

Signatures of Dobzhansky-Muller Incompatibilities in the Genomes of Recombinant Inbred Lines.

Genetics - 1 Feb 2016

Colomé-Tatché Maria, Johannes Frank

Abstract excerpt

In the construction of recombinant inbred lines (RILs) from two divergent inbred parents certain genotype (or epigenotype) combinations may be functionally "incompatible" when brought together in the genomes of the progeny, thus resulting in sterility or lower fertility. Natural selection against these epistatic combinations during inbreeding can change haplotype frequencies and distort linkage disequilibrium...

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Identifiers

PMID: 26680662
DOI: 10.1534/genetics.115.179473
PMCID: PMC4788252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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