Article
A 6-bp deletion in exon 8 and two mutations in introns of TYRP1 are associated with blond coat color in Liangshan pigs.
Gene - 1 Mar 2016
Wu Xiaoqian, Zhang Yi, Shen Linyuan, Du Jingjing, Luo Jia, Liu Chendong, Pu Qiang, Yang Runlin, Li Xuewei, Bai Lin, Tang Guoqing, Zhang Shunhua, Zhu Li
Abstract excerpt
Melanocortin receptor 1 (MC1R), Agouti signaling protein (ASIP), and Tyrosinase-related protein 1 (TYRP1) are reported critical genes that regulate pheomelanin and eumelanin synthesis in mammals. Liangshan pig is a special Chinese indigenous pig breed with two completely different coat colors, solid black and blond. In this study, we detected polymorphisms of the above three genes and assessed the relationships...
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