Article
Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis.
Journal of immunology research - 1 Jan 2015
Khanam Irin Afroza, Kodamullil Alpha Tom, Gündel Michaela, Hofmann-Apitius Martin
Abstract excerpt
Neurodegenerative as well as autoimmune diseases have unclear aetiologies, but an increasing number of evidences report for a combination of genetic and epigenetic alterations that predispose for the development of disease. This review examines the major milestones in epigenetics research in the context of diseases and various computational approaches developed in the last decades to unravel new epigenetic...
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