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Article

Effects of Long-Term Type I Interferon on the Arterial Wall and Smooth Muscle Progenitor Cells Differentiation.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2016

Diao Yanpeng, Mohandas Rajesh, Lee Pui, Liu Zhiyu, Sautina Larysa, Mu Wei, Li Shiyu, Wen Xuerong, Croker Byron, Segal Mark S

Abstract excerpt

OBJECTIVE: Patients with systemic lupus erythematosis are at risk for premature atherosclerosis and half of the patients with systemic lupus erythematosis have elevated type I interferon (IFN-I) levels. We hypothesized that IFN-I would induce premature atherosclerosis by increasing the number of smooth muscle progenitor cells (SMPC) in the bloodstream and promoting atherosclerotic lesions within the vasculature....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26634654
DOI: 10.1161/ATVBAHA.115.306767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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