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Evaluation of a microfluidic-based point-of-care prototype with customized chip for detection of bacterial clusters.

Microbiology spectrum - 5 Dec 2024

Treffon Janina, Isserstedt-John Nicole, Klemm Richard, Gärtner Claudia, Mellmann Alexander

Abstract excerpt

Bacterial infection clusters cause high mortality rates and healthcare costs due to excessive therapy and hygiene measures. The aim of this study was to develop an automated real-time PCR-based point-of-care (POC) system with a customized microfluidic chip that facilitates fast detection of bacterial cluster isolates by targeting cluster-specific single-nucleotide polymorphisms (SNPs). For cluster detection of...

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Acinetobacter baumannii
Bacteria
Bacterial Infections
Lab-On-A-Chip Devices
Microfluidics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Point-of-Care Systems

Real-Time Polymerase Chain Reaction

Staphylococcus aureus

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Identifiers

PMID: 39503490
DOI: 10.1128/spectrum.00862-24
PMCID: PMC11619353

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