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The Presence of Phage Orthologous Genes inHelicobacter pyloriCorrelates with the Presence of the Virulence FactorsCagAandVacA

27 Nov 2015

Abstract excerpt

BACKGROUND: The bacterium Helicobacter pylori is associated with ulcers and the development of gastric cancer. Several genes, including cytotoxin-associated gene A (CagA) and vacuolating cytotoxin A (VacA), are associated with increased gastric cancer risk. Some strains of H. pylori also contain sequences related to bacteriophage phiHP33; however, the significance of these phage-related sequences remains unknown....

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PMID: 26612095
DOI: 10.1111/hel.12282

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