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Article

Aristaless-Like Homeobox protein 1 (ALX1) variant associated with craniofacial structure and frontonasal dysplasia in Burmese cats.

Developmental biology - 15 Jan 2016

Lyons Leslie A, Erdman Carolyn A, Grahn Robert A, Hamilton Michael J, Carter Michael J, Helps Christopher R, Alhaddad Hasan, Gandolfi Barbara

Abstract excerpt

Frontonasal dysplasia (FND) can have severe presentations that are medically and socially debilitating. Several genes are implicated in FND conditions, including Aristaless-Like Homeobox 1 (ALX1), which is associated with FND3. Breeds of cats are selected and bred for extremes in craniofacial morphologies. In particular, a lineage of Burmese cats with severe brachycephyla is extremely popular and is termed...

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Source

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Identifiers

PMID: 26610632
DOI: 10.1016/j.ydbio.2015.11.015
PMCID: PMC4724490

Genes

ALX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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