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Article

Extracellular cleavage of collagen XVII is essential for correct cutaneous basement membrane formation.

Human molecular genetics - 15 Jan 2016

Nishimura Machiko, Nishie Wataru, Shirafuji Yoshinori, Shinkuma Satoru, Natsuga Ken, Nakamura Hideki, Sawamura Daisuke, Iwatsuki Keiji, Shimizu Hiroshi

Abstract excerpt

In skin, basal keratinocytes in the epidermis are tightly attached to the underlying dermis by the basement membrane (BM). The correct expression of hemidesmosomal and extracellular matrix (ECM) proteins is essential for BM formation, and the null-expression of one molecule may induce blistering diseases associated with immature BM formation in humans. However, little is known about the significance of...

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Identifiers

PMID: 26604146
DOI: 10.1093/hmg/ddv478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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