Article
Trichomonas vaginalis Lipophosphoglycan Exploits Binding to Galectin-1 and -3 to Modulate Epithelial Immunity.
The Journal of biological chemistry - 8 Jan 2016
Fichorova Raina N, Yamamoto Hidemi S, Fashemi Titilayo, Foley Evan, Ryan Stanthia, Beatty Noah, Dawood Hassan, Hayes Gary R, St-Pierre Guillaume, Sato Sachiko, Singh Bibhuti N
Abstract excerpt
Trichomoniasis is the most common non-viral sexually transmitted infection caused by the vaginotropic extracellular protozoan parasite Trichomonas vaginalis. The infection is recurrent, with no lasting immunity, often asymptomatic, and linked to pregnancy complications and risk of viral infection. The molecular mechanisms of immune evasion by the parasite are poorly understood. We demonstrate that galectin-1 and...
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