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Article

Transdifferentiation of periodontal ligament-derived stem cells into retinal ganglion-like cells and its microRNA signature

9 Nov 2015

Abstract excerpt

Retinal diseases are the leading causes of irreversible visual impairment and blindness in the developed countries. Human retina has limited regenerative power to replace cell loss. Stem cell replacement therapy has been proposed as a viable option. Previously, we have induced human adult periodontal ligament stem cells (PDLSCs) to the retinal lineage. In this study, we modified our induction protocol to direct...

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PMID: 26549845
DOI: 10.1038/srep16429

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